About Us
VPC NeuroTherapeutics Inc. is a start-up pharmaceutical company at the preclinical/clinical stage, established by Dr. Kwiecien in 2021 in Hamilton, Ontario, Canada to develop, obtain regulatory approvals and market effective treatments for severe, destructive inflammatory disease initiated by neurotrauma and stroke.
Dr. Kwiecien's systematic studies led to elucidation of the pathogenesis of this disease and to identification of the therapeutic target: severe inflammation which not only causes additional destruction in the injured spinal cord but also damages blood vessels in not-yet-destroyed tissue, causing excessive leaking, swelling, and paralysis.
The oral administration of xanthohumol, a small flavonoid molecule isolated from hops, inhibits the severity of neuroinflammation, shortens its course, and preserves spinal cord from destruction. The anti-neuroinflammatory effect of xanthohumol is proprietary.
In a recent clinical study by Dr. Dabrowski in Lublin, Poland, its anti-inflammatory activity consistently resulted in recovery of motor function in spinal cord injury patients, attributed to inhibition of vascular damage and elimination of swelling. Unprecedented.
The company is engaged in regulatory approvals for an oral formulation with synthesized xanthohumol in preclinical studies and clinical trials towards completion of Clinical Trial Phase 2, anticipated in 4 years.
Key Facts
FoundedLocationHamilton, Ontario, Canada
Preclinical / Clinical
StageFounderLead Drug2021
Dr. Jacek M. Kwiecien
VPCnt-101
Licensing Opportunities
Explore ways to work with us.
“Treatment of Neuroinflammation”
USPTO18805174
PCT/CA2025/051062
WO 2026/036211 A1
Anti-inflammatory activity of grain protein administered orally.
Licensing leading to development of a bio-active food supplement with neuroprotective activity in the brain and spinal cord specifically suitable for long term improvement of function in aging/ailing brain.
Leadership & Advisors
Dr. Jacek M. Kwiecien
DVM, MSc, PhD
Veterinarian with training in veterinary pathology and multidirectional research interests. 30 years of education in 4 different languages in Poland, France, Canada, and the USA. Discoveries resulting in 2 patents, 80 peer-reviewed manuscripts, 1 book, and a cure for a severe disease initiated by neurotrauma and stroke. Established and validated novel animal models of SCI, selected xanthohumol as an oral effective treatment.
President, CEO, CSOWojciech Dabrowski
MD, PhD
Professor and Chair, Department of Anaesthesiology and Intensive Care, Medical University of Lublin, Poland. Oversees clinical studies in Poland.
Clinical AdvisorInvestor RelationsBruce McKay
MBA
Investor affairs and fundraising. Investor at AngelONE, Burlington, ON. Former Vice President at TD Bank.
Regulatory AffairsAnna Metcalfe
RAC
Over 35 years of experience in global regulatory affairs and bringing innovative products to market.
Partner at L2 Consultants Inc., specializing in toxicology.
ToxicologyLeigh Berryman
BSc
ManufacturingRichard L. Wilcocks
MSc
President of RLW Consulting, specializing in CMC and cGMP manufacture.
Preclinical research assistant: neurosurgeries, drug dosing, animal care, perfusions, and data integration.
Preclinical ResearchKathleen H. Delaney DVM, Dip. Pathol.
Scientific data integration, presentation, and analysis. Website management.
Data & TechnologyChristian J. Kwiecien-Delaney
BSc.(Hons.)
Over 40 years of pharmaceutical industry executive experience.
Advisor, Business DevelopmentJohn J. Seman
MSc
Partner at ITC Plus, Inc. Specializes in Scientific Research & Experimental Development programs.
SR&EDMichael Gogolev
P.Eng., PhD
ResearchBryce Kwiecien-Delaney
BA, Psychology
Pe-clinical research assistant.